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†Individual results may vary.
Wegovy® (semaglutide) injection 2.4 mg is an injectable prescription medicine used with a reduced calorie diet and increased physical activity, to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight and that may help adults and children aged 12 years and older with obesity, or some adults with overweight who also have weight-related medical problems, to help them lose excess body weight and keep the weight off.
Wegovy®, along with a reduced calorie diet and increased physical activity, is used to help children aged 12 years and older with obesity to lose excess body weight and keep it off.
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Managing Weight With Wegovy®
If you're struggling with weight loss, you're not alone. Learn about losing weight and keeping it off with Wegovy® along with a reduced calorie diet and increased physical activity.
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Losing weight with Wegovy®*
Weight loss with Wegovy® has been measured in several medical studies. Take a look at the results from one of the studies that lasted about 1 year and 4 months (68 weeks).
The study included
Adults with either obesity or overweight with a weight-related medical condition
Adults were randomly placed into 2 groups
Everyone was instructed to follow a reduced-calorie diet and increase their physical activity.
The results showed
Adults taking Wegovy® lost more weight than those taking placebo.
Adults who took Wegovy® achieved on average 15% weight loss
~232 lb starting weight
Adults who took placebo achieved on average ~2.5% weight loss
~232 lb starting weight
What else did the results show?
Everyone is different, but let's dig deeper into the data to get some insight.
83% or about 8 in 10 adults achieved
5% or more weight loss with Wegovy®
compared with 31% taking placebo
66% or about 6 in 10 adults achieved
10% or more weight loss with Wegovy®
compared with 12% taking placebo
48% or about half of adults achieved
15% or more weight loss with Wegovy®
compared with 5% taking placebo
And that’s not all—some adults lost even more weight
About 1 in 3 adults achieved 20% weight loss
based on ~232 lb starting weight
30% of adults (about 1 in 3) taking Wegovy® lost 20% or more weight compared with 2% of adults on placebo. This result was not the primary goal of the study and should be considered as additional information.
Individual results may vary.
*Results are from a 68-week medical study of adults with either obesity (BMI ≥ 30) and adults with overweight (BMI ≥ 27) who also had weight-related medical problems, including high blood pressure or high cholesterol. Adults with type 2 diabetes were excluded. During the trial, 17% of adults in the Wegovy® group discontinued treatment compared with 22% of adults in the placebo group.
Discover your potential weight loss with Wegovy®†
Wondering what the study results discussed above might look like for you? See how much weight you could lose while taking Wegovy® along with a reduced calorie diet and increased physical activity.
-10lb
–If you lose 5% of your current weight
-20lb
–If you lose 10% of your current weight
-30lb
–If you lose 15% of your current weight
-40lb
–If you lose 20% of your current weight
Your potential weight loss results are based on the study explained above.
Why 5%? In the study discussed above, 83% of adults taking Wegovy® lost 5% or more body weight, compared with 31% of adults taking placebo.
Why 10%? In the study discussed above, 66% of adults taking Wegovy® lost 10% or more body weight, compared with 12% of adults taking placebo.
Why 15%? In the study discussed above, adults on average achieved 15% weight loss while taking Wegovy®, compared with 5% of adults taking placebo.
Why 20%? In a supportive measure of the same study discussed above, ~30% of adults taking Wegovy® lost 20% or more weight compared with ~2% of adults taking placebo.
Talk to your health care professional about a goal weight that is healthy & realistic for you.
Health care professionals prescribe Wegovy® to help with losing weight and keeping it off in adults living with obesity and some with overweight and weight-related medical problems.
Benefits beyond the scale‡
While not approved to treat these conditions, adults taking Wegovy® experienced improvements in:
Waist size
Blood pressure
Cholesterol
Blood sugar
Some adults taking Wegovy® experienced an increase in resting heart rate.
‡Results are from a 68-week medical study of adults with either obesity (BMI ≥ 30) and adults with overweight (BMI ≥ 27) who also had weight-related medical problems, including high blood pressure or high cholesterol. Adults with type 2 diabetes were excluded. Both groups received instruction for a reduced calorie diet and increased physical activity.
Keeping the weight off with Wegovy®
Take a look at 2 more studies. One study measured weight change when adults taking Wegovy® either stayed on Wegovy® or switched to placebo.§ Another study followed weight maintenance in adults taking Wegovy® over the course of 2 years.‖
Why stay on Wegovy®?§
In a medical study that lasted about 1 year and 4 months (68 weeks), everyone took Wegovy® for the first 5 months (20 weeks) while also reducing calories and increasing physical activity.
At month 5 (week 20), adults were divided into 2 groups: One group continued taking Wegovy®, while the other group switched to placebo.
From month 5 through the end of the study, adults who stayed on Wegovy® continued to lose weight, while the adults taking placebo gained weight.
§This medical study included 902 adults with either obesity (BMI ≥ 30) or overweight (BMI ≥ 27) with at least 1 weight-related condition. Adults with type 2 diabetes were excluded. In the first 20 weeks, everyone started taking Wegovy®. Of these 902 adults, 803 were able to reach the 2.4-mg dose and were randomized to stay on Wegovy® (535 adults) or switch to placebo (268 adults). After week 20, 5.8% of participants taking Wegovy® discontinued treatment compared with the 11.6% taking placebo. Adults who continued taking Wegovy® lost an additional 7.9% of their body weight on average while those who switched to placebo gained 6.9% body weight on average. Everyone was instructed to follow a reduced calorie diet and increase their physical activity throughout the length of the study.
Adults taking Wegovy® achieved lasting weight loss in a separate 2-year medical study‖
Proven to maintain weight loss
- On average, adults taking Wegovy® lost ~15% (~35 lb) vs 2.6% (~6 lb) of adults taking placebo
- Majority of adults taking Wegovy® (77%) lost 5% or more weight compared with 34% taking placebo
- Average starting weight for adults taking Wegovy® was ~233 lb, and for those taking placebo, it was ~235 lb
‖This 2-year medical study included 304 adults with either obesity (BMI ≥ 30) or overweight (BMI ≥ 27) with at least 1 weight-related medical condition. Adults with diabetes were excluded. Everyone received instruction for a reduced calorie diet and increased physical activity. During the trial, 13% of participants taking Wegovy® discontinued treatment compared with 27% taking placebo.
In general, those who stopped taking Wegovy® regained weight
Explore the science behind Wegovy®
Get a better understanding of how Wegovy® helps people lose weight and keep it off.
Ready to manage your weight? Talk to your health care professional to see if Wegovy® is right for you
Your health care professional is a medical expert, but when it comes to your experience, you know best. See the Wegovy® Medication Guide on the FDA-approved uses of Wegovy®.
Use the Weight-Management Conversation Guide to help you
- Decide what you want to share during your next appointment
- Make a list of questions you have about your treatment
- Get tips to help you keep the conversation on track
Personalized support for adults taking Wegovy®
WeGoTogether® is your support partner while you're taking Wegovy®, giving you a choice of features, like coaching and progress-tracking tools, to help you set achievable goals and stay motivated.
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Questions?
Need assistance or information?
Call the Wegovy® Navigation Line at 1-833-4-WEGOVY (1-833-493-4689) between 9:00 AM and 6:00 PM ET, Monday–Friday.
