Wegovy® (semaglutide) injection 2.4 mg is an injectable prescription medicine used with a reduced calorie diet and increased physical activity, to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight and that may help adults and children aged 12 years and older with obesity, or some adults with overweight who also have weight-related medical problems, to help them lose excess body weight and keep the weight off.
Wegovy®, along with a reduced calorie diet and increased physical activity, is used to help children aged 12 years and older with obesity to lose excess body weight and keep it off.
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Using the Wegovy® Pen
Wegovy® is a once-weekly injection. It is taken on the same day each week, at any time of day, with or without food.
Before using the Wegovy® pen for the first time, discuss how to prepare and inject Wegovy® with your health care professional. Also, be sure to read the full Instructions for Use.
Get to know your Wegovy® pen
Wegovy® comes in a single-use pen with a preset dose, so you'll use a new pen every time you take Wegovy®.
Wegovy® pen parts
See the Wegovy® pen in action
Click or tap the arrows below to get an idea of what the Wegovy® pen will look like while you’re using it, and how to know when the injection is complete. Be sure to review the full Instructions for Use for step-by-step instructions.
Trust what you’re taking is authentic Wegovy®
To confirm you have Wegovy®, make sure it
- Is NOT in a vial
- Has an 11-digit National Drug Code (NDC) on the pen and the box it came in
- Has a lot number on the pen and the box it came in
If you have any concerns about the authenticity of the medicine, do not take it. Instead, call your health care professional or Novo Nordisk (1-800-727-6500) to confirm.
Watch the demonstration video
This video is based on the Instructions for Use that come with your Wegovy® pen.
You should store Wegovy® in the refrigerator. If needed, however, Wegovy® can be kept outside of the refrigerator between 46 °F and 86 °F for up to 28 days. Keep Wegovy® in the original carton to protect it from light. Throw away the pen if Wegovy® has been frozen. You may consider leaving your pen out to reach room temperature before using it. Make sure to leave the cap on your pen during this time.
Before you use your Wegovy® pen for the first time, make sure you read the Instructions for Use and Medication Guide that come with your pen, and that you talk to your health care provider about how to prepare for and inject Wegovy® correctly.
In each pack of Wegovy®, you’ll get 4 pens that are all the same dose. You will use 1 pen each week, on the same day each week at any time of day. Each pen is for one-time use only and comes with a preset dose. The needle is covered and will not be seen.
Now let’s talk about how to use your Wegovy® pen. We’ll discuss preparation, injection, and disposal.
To prepare, start by washing your hands. Next, let’s check a few things.
Make sure the pen indicates the correct medication and dose your health care provider prescribed. Check the pen window to make sure the medicine is clear and colorless. Do not use your Wegovy® pen if the pen appears to have been used or any part of the pen appears broken (for example, if the pen has been dropped) or if the expiration date on the back has passed. If you notice any of these things, call 1-833-934-6891. Today I’m demonstrating with the 0.25 mg pen, which is the first dose you’ll start on with Wegovy®.
Next, your health care provider can help you choose the injection site that is best for you. This can be your upper legs, lower stomach, or upper arms. You can inject Wegovy® in the same part of your body each week, but make sure it is not in the exact same spot each time.
Make sure to clean your injection site with an alcohol swab or soap and water, and don’t touch the area after cleaning. Allow your skin to dry before injecting.
Now let’s walk through the injection from start to finish.
Remove the pen cap by pulling it straight off your Wegovy® pen. It may help to create a firm area to inject. Line up the pen straight against your injection site so you can clearly see the pen’s window.
To start the injection, push the pen firmly against your skin. Make sure you continue pressing the pen firmly against your skin for the entire injection, which should take about 10 seconds.
When you hear the first click, the injection has started and the yellow bar in the pen window should start moving. If you do not hear the first click and the yellow bar does not start moving, press the pen more firmly against your skin. When the injection is still in progress, you will hear a second click. The second click means the injection is ongoing. So, keep applying pressure until the yellow bar stops moving.
The pen window will look like this when the injection is complete. The yellow bar will not fill the entire pen window. Do not remove the pen from your skin before the yellow bar in the pen window has stopped moving. Once you’re done with your injection, slowly lift the pen away from your skin.
If you’re experiencing difficulties injecting, you can switch to a more firm injection site, such as your upper leg or upper arm. Or consider standing up while injecting into the lower stomach.
If the pen is removed from your skin too early or you have not pressed the pen firmly against your skin for the entire injection, medication may appear on the skin or squirt from the needle, and you may not get your full dose. Make sure the next time you inject to keep applying pressure until the yellow bar stops moving. Then you can lift the pen slowly from your skin.
Now it’s time to safely throw away or dispose of your pen. Do not throw the pen away in your household trash. Instead, use an FDA-cleared sharps disposal container or a sturdy household container with a tight-fitting lid, like a heavy-duty plastic container. Contact your local municipality to find where you can dispose of needles.
And that’s it–you’re done! Now you’re ready to start using your Wegovy® pen. You’ve got this!
And remember: we’re here for you! If you have any questions, call 1-833-4-WEGOVY.
Please note that this video specifically pertains to the US Pen device and should not be used for any other pen devices. If there is any uncertainty, check your device and its label to ensure proper usage.
Let’s recap: 5 steps for using your Wegovy® pen
Prepare for the injection
Choose the injection site
Remove
pen cap
Inject
Wegovy®
Throw away
the pen
Prepare for the injection
- Gather your supplies: Your Wegovy® pen, 1 alcohol swab or soap and water, 1 gauze pad or cotton ball, and 1 heavy-duty plastic container with a tight-fitting lid for your used Wegovy® pen
- Wash your hands
- Check the Wegovy® pen
Do not use the pen if:
- It appears to have been used
- Any part appears broken
- The Wegovy® medicine is not clear and colorless through the pen window (air bubbles are normal)
- The expiration date (EXP) has passed
Choose the injection site
Your health care professional can help you choose the injection site that is best for you.
- You may inject into your upper leg (front of the thigh), lower stomach (keep 2 inches away from your belly button), or upper arm—but make sure you can clearly see the pen window while injecting
- Do not inject into an area where the skin is tender, bruised, red, or hard. You should also avoid injecting into areas with scars or stretch marks
- You may inject into the same body area each week, but not in the exact same spot each time
Before taking Wegovy®, clean your chosen injection site with an alcohol swab or soap and water.
Do not touch the injection site after cleaning. Allow the skin to dry before injecting.
Remove the pen cap
- Pull the pen cap straight off your pen
- The needle is hidden, so you don't have to see or handle it
- Just because you can't see it, doesn't mean it isn't there! Be careful not to push down on the needle cover to avoid needle stick injuries
Inject your Wegovy® dose
Push the pen firmly against your skin and keep applying pressure.
You'll know your injection has started when the yellow bar starts moving. If you don't see it moving, press the pen more firmly against your skin.
The injection should take about 5-10 seconds
Don't stop after 2 clicks. You will hear 2 clicks during the injection
- Click 1: The injection has started
- Click 2: The injection is ongoing, not finished
Do not remove the pen from your skin until the yellow bar stops moving and 10 seconds have passed. Then, lift the pen slowly away from your skin.
Safely throw away your pen
After injecting your Wegovy® dose, you don’t want to throw away the pen in your household trash or recycling bin. Instead, use either
- An FDA-cleared sharps disposal container
- A sturdy household container with a tight-fitting lid, like a heavy-duty plastic container. Make sure the container is properly labeled to warn of hazardous waste inside
You can request a complimentary sharps disposal container from Novo Nordisk. Learn more
How you dispose of your sharps container is also important. Follow the guidelines for where you live. To find a sharps disposal location near you, visit safeneedledisposal.org.
Learn more in the Wegovy® Medication Guide.
What if blood appears after the injection?
If blood appears at the injection site, press lightly with a gauze pad or cotton ball.
| Short on time? Get the Wegovy® Quick Start Guide |  |
Troubleshooting
- If you have problems injecting, change to a more firm injection site, such as the upper leg or upper arm. Otherwise, consider standing up while injecting into the lower stomach
- If medicine appears on the skin or squirts from the needle, you may not have received your full dose. You cannot restart the injection, so ask your health care professional what they recommend. The next time you inject, make sure you
- Keep applying pressure until the yellow bar stops moving
- Lift the pen slowly from your skin after the injection is complete
Wegovy® pen care, storage, and disposal
Still have questions?
For immediate assistance, the Wegovy® Navigation Line is available Monday through Friday, 9:00 am to 6:00 pm ET.
Call 1-833-4-WEGOVY (1-833-493-4689)
For free ongoing support, partner with WeGoTogether® to help you get started and stay on track with Wegovy®.
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Questions?
Need assistance or information?
Call the Wegovy® Navigation Line at 1-833-4-WEGOVY (1-833-493-4689) between 9:00 AM and 6:00 PM ET, Monday–Friday.
